Mutation Surveyor Video Tutorials

Mutation Surveyor® DNA Variant Analysis Software

Mutation Surveyor® is an advanced software tool designed to provide high-accuracy DNA sequencing analysis.

Developed by SoftGenetics, it is widely used for variant detection in Sanger sequencing data, with capabilities to detect Single Nucleotide Polymorphisms (SNPs), insertions, deletions (indels), and somatic mutations. With patented anti-correlation technology, Mutation Surveyor achieves up to 99.5% accuracy and a sensitivity of 5% for the primary peak, ensuring precise variant analysis.

Mutation Surveyor makes your sequencing data interpretation faster and more reliable. Below is a list of video resources designed to help you master the features and functionalities of Mutation Surveyor.

Mutation Surveyor Video Tutorials

Getting Started with Mutation Surveyor 

• Mutation Surveyor Introductory Overview
  Get started with Mutation Surveyor and understand the core features that make it a powerful tool for DNA variant analysis.

• Working With Your Mutation Surveyor Project in the Graphical Analysis Display Part I: GAD Basics
  Learn the basics of the Graphical Analysis Display (GAD) interface and how to navigate your projects within it.

• Working With Your Mutation Surveyor Project in the Graphical Analysis Display Part II: Getting to Know the Sample Traces Pane
  Familiarize yourself with the Sample Traces Pane, an essential feature for analyzing sequencing data.

• Working With Your Mutation Surveyor Project in the Graphical Analysis Display Part III: Editing in the GAD
  Discover how to make edits in the Graphical Analysis Display for precise variant identification and data adjustments.

Data Review and Variant Detection

• Het_Indel Detection Part 1 & Part 2
  Master the detection and analysis of heterozygous insertions and deletions (indels) across your sequencing data.

• Reviewing and Editing Data-Part 1 & Part 2
  Learn how to review and edit your sequencing data effectively to ensure the most accurate variant calls.

• Low Frequency Variant Detection
  Learn how to detect low-frequency variants with high sensitivity, crucial for applications in rare variant detection.
• Analysis and Reporting of Delins Variants
  Learn how to analyze and report deletion-insertion variants (delins) within your sequencing data.
• Mutation Quantification with Mutation Surveyor Software
  Understand how to perform mutation quantification to assess the prevalence and frequency of mutations in your samples.

 Optimizing and Customizing Analysis Settings 

• Quality Values in Mutation Surveyor Software
  Understand how to interpret quality values and improve your analysis by leveraging the software's built-in quality control tools.

• Optimizing Analysis Settings Part 1 & Part 2
  Learn how to optimize your analysis settings for better variant detection and accuracy across projects.

• Creating Custom Settings Files
  Discover how to create and save custom settings that can streamline the analysis of similar sequencing projects.

• Utilizing Amplicon IDs for Grouping of Complex and Overlapping Regions
  Master the use of Amplicon IDs to group complex and overlapping regions in your sequencing data for more efficient analysis. 

Analysis and Specialized Tools 

• Mitochondria Analysis with Mutation Surveyor Software
  Get insights into mitochondrial DNA sequence analysis, an essential tool for studying mitochondrial mutations and diseases.

• Methylation Sequence Analysis Using Mutation Surveyor Software
  Learn how to detect DNA methylation patterns using the specialized tools in Mutation Surveyor.
• Mutation Surveyor AutoRun Tool
  Discover how to automate your analysis with the AutoRun Tool, allowing for continuous and efficient processing of large data sets.

• Gene Transcript Selection in Mutation Surveyor Software
  Master the process of selecting the appropriate gene transcripts to ensure accurate variant detection in your projects.

External Database and GenBank Integration 

• Application of Annotation from External Databases to Mutation Surveyor Projects
  Learn how to integrate annotation from external databases like dbSNP, ClinVar, and gnomAD to enhance your variant analysis.

• Creating a User Knowledge Database of Known Artifacts and False Positives
  Build a database of known artifacts and false positives to improve the accuracy of future analyses.

• Reference Assembly with Mutation Surveyor Software
  Learn how to align your sequencing traces to reference assemblies like GRCh37 or GRCh38 for accurate variant calling.

• Downloading GenBank Reference Files for Mutation Surveyor Software
  Get instructions on downloading and utilizing GenBank reference files for assembly and variant detection.

• Creating ROI and Editing GenBank Files
  Discover how to define Regions of Interest (ROI) and edit GenBank files for better variant analysis and reporting.
• Reference & Track Manager Tool
  Learn how to use the Reference & Track Manager Tool to organize, compare, and manage your sequencing data more effectively.

Custom Reporting 

• Custom Report Options
  Explore how to generate custom reports with specific data and analysis results, tailored to your needs

Why Choose Mutation Surveyor?

Mutation Surveyor is an invaluable tool for genetic researchers and professionals working with Sanger sequencing data. With its powerful features, including custom reporting, variant knowledge databases, and methylation analysis, Mutation Surveyor ensures that your analysis is accurate, efficient, and insightful. Its ability to handle large datasets (up to 2000 files in 15 minutes) makes it ideal for high-throughput environments.

Additionally, Mutation Surveyor is equipped with robust security features, including user management and audit trails, providing full control over data access and project integrity.

Get Started with Mutation Surveyor

Ready to see how Mutation Surveyor can improve your DNA sequencing analysis?
Download a free 35-day trial today and explore the powerful capabilities of Mutation Surveyor.